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Annual report 2008, Menzies School of Health Research



Annual report 2008, Menzies School of Health Research

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Menzies School of Health Research annual report 2008; 2008 Menzies School of Health annual report


Menzies School of Health Research


E-Publications; E-Books; PublicationNT; Menzies School of Health Research annual report; Annual Report






Through scientifi c excellence, education and research the team at Menzies is discovering ways to reduce the impact of disease and improve the health and well-being of people living in Australia and beyond. -- page 4


Made available via the Publications (Legal Deposit) Act 2004 (NT).; Charles Darwin University; Discovery for a healthy tomorrow

Table of contents

Who we are and what we do page 4 -- Where and how we work page 5 -- Menzies Strategic Plan page 6 -- Vision page 7 -- Values page 7 -- Goals page 7 -- The Year at a Glance page 8 -- Financial and Corporate Overview page 12 -- A Message from the Chair page 14 -- A Message from the Director page 16 -- A Message from the Indigenous Development Unit page 18 -- Child Health Division page 21 -- Healing and Resilience Division page 27 -- International Health Division page 33 -- Preventable Chronic Diseases Division page 39 -- Services, Systems and Society Division Page 45 -- Tropical and Emerging Infectious Diseases Division page 51 -- Education and Training Division page 57 -- Corporate Services Division page 63 -- Menzies and the Community page 71 -- Governance page 72 -- Honorary Appointees page 75 -- Research Funding page 76 -- Publications page 84 -- Professional Activities page 92 -- Collaborators page 96 -- page 3




Menzies School of Health Research; Medicine; Research; Annual report

Publisher name

Menzies School of Health Research

Place of publication



Menzies School of Health Research annual report; Annual Report




99 pages : colour illustration ; 30 cm.

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Copyright owner

Menzies School of Health Research



Related links

https://www.menzies.edu.au/ [Menzie School of Health Research website]

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Tropical and emerging infectious diseases division Research Priorities The Tropical and Emerging Infectious Diseases Division will continue to investigate specifi c illnesses of priority and monitor emerging infectious diseases in Indigenous people and others living in tropical and remote environments. The Divisions research portfolio covers skin health, scabies and streptococci; melioidosis and emerging infectious diseases; local impacts of global climate change; adult respiratory health; and tropical toxinology. The Division will focus on the prevention, diagnosis and treatment of current and emerging diseases. Epidemiology, clinical observations and basic laboratory work are interlinked with our multi-discipline approach to seeking a better understanding of the underlying disease processes and the complex infl uences over our unique and changing environment. Importantly, the research of this Division, along with that of the International Health Division, will continue to strengthen Australias capacity to prevent and respond to emerging tropical health threats in our region. Looking Forward The Division is moving into particularly productive and exciting times. Divisional tropical toxinology researchers are coordinators of the prospective Australian Snake bite project, which will translate recent results into revised guidelines for the use of antivenoms in the treatment of snake bite and improved methods of fi rst aid. Melioidosis researchers will continue to consolidate their position as world leaders in the understanding and treatment of this disease. Research to be carried out in the next 1-2 years and funded by the US National Institutes of Health will make use of the superb collection of Burkholderia pseudomallei isolates held at the Menzies to identify genes associated with virulence and different forms of melioidosis. This will form the basis of gene-based smart diagnostics that can be used directly on clinical samples. The other major direction of the melioidosis group is the identifi cation of environmental drivers of this disease. The melioidosis map will be refi ned and factors, both natural and non-natural, that impact on the risk of disease will be identifi ed. This work will be translated into guidelines for rural and urban land use and development. Research into the major skin pathogens continues apace, with the principal focus in the immediate future being the commercialisation of a scabies immunodiagnostic, and the determination of the genome make ups, population structures and patterns of dissemination of the two major communuty acquired Staphylococcus aureus strains in the Top End. Finally, Divisional reseachers have developed a rapid approach to genotyping bacteria. It is very cheap and robust, and the results can be thoroughly analysed and put into context using bioinformatics. The aim is that this will be transferred to end users, and underpin the development of a unifi ed web-based bacterial genotyping method that is routinely used by most if not all health deartments. If possible and appropriate, this will involve commercial arrangements. Melioidosis and Emerging Infections Melioidosis clinical and diagnostic studies in the NT. Molecular studies of Burkholderia pseudomallei. Presence of the Melioidosis bacterium in bore water in rural Darwin. Risk assessment for presence of Burkholderia pseudomallei in NT waters. Using real time PCR to detect the ecological niches of Melioidosis bacteria Burkholderia pseudomallei in endemic tropical Australia. High-resolution/highly sensitive assays for forensic analysis and attribution of bacterial biothreat agents. Surveillance for emerging infectious diseases. Adult Respiratory Health Selective use of long-term antibiotics for chronic lung obstructive disease in Aboriginal adults. Tropical Toxinology Australian Snakebite Project. Top End Prospective Jellyfi sh Study. Prospective evaluation of terrestrial and marine envenoming in humans: clinical effects, predictors of severity, toxicokinetics and potential treatments. Molecular toxinology of Australian box jellyfi sh venoms. A randomised controlled trial of factor replacement therapy in snake bite coagulopathy. Research Projects 52 Menzies School of Health Research | Annual Report 2008

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